Abstract: This dissertation explores how Canadian drug laws impact Indigenous sovereignty andperpetuate settler colonialism. It analyzes cannabis, liquor, and tobacco regulations to show howthey have historically undermined Indigenous rights. The first chapter examines cannabis lawsfrom 1923 to the 2018 Cannabis Act, revealing how these laws limit Indigenous control andcriminalize resistance. The second chapter discusses liquor laws from the late 1800s to the early1900s, highlighting how they shaped white settler identities by penalizing those who interactedwith Indigenous people. The third chapter critiques the Canadian tobacco industry’s portrayal ofthe Mohawk tobacco trade as illegal, showing how this benefits the industry economicallythrough the criminalization of Indigenous peoples. Drawing on Settler Colonial Theory, CriticalRace Theory, and Indigenous Criminology, this study uncovers the complex ways colonialpower dynamics operate, helping us understand how drug laws continue to control Indigenouspeoples and legitimize the theft of their lands.